Somatostatin-28

Not For Human Use, Lab Use Only.

C137H207N41O39S3

SKU KSP-25106 Category

Sequence 3 letters:

H-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH

Sequence:

SANSNPAMAPRERKAGCKNFFWKTFTSC

Cas No. :

Molecular Formula:

C137H207N41O39S3

Molecular Weight:

3148.6

Description

This octacosapeptide S-28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a larger precursor, preprosomatostatin. S-28 was first isolated from porcine duodenum. In guinea-pig pancreatic acini, S-28, unlike S-14, increased amylase secretion, cellular cyclic GMP, and Ca2+ outfluxes.

Reference

  • L.Pradayrol et al., FEBS Lett., 109, 55 (1980)
  • A.V.Schally et al., Proc. Natl. Acad. Sci. USA, 77, 4489 (1980)
  • N.Tahiri-Jout et al., Neuropeptides, 19, 65 (1991)
  • G.Bissette and B.Myers, Life Sci., 51, 1389 (1992)
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