Sequence 3 letters:

H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Pro-Arg-Tyr-NH2

Sequence:

YPSKPDNPGEDAPAEDLARYYSALRHYINLITRPRY

Cas No. :

Molecular Formula:

C₁₉₀H₂₈₆N₅₄O₅₆

Molecular Weight:

4222.69

Description

(Pro34)-NPY is a selective NPY agonist at Y1 or postjunctional receptors, as seen in a simultaneous study of post- and prejunctional actions in anesthetized rats and dogs. Like NPY, the analog increased blood pressure, but, in contrast, showed no inhibitory effects on cardiac vagal action.

Reference

• E.K.Potter et al., Eur. J. Pharmacol., 193, 15 (1991)