Sequence 3 letters:

H-Ile-Asn-Pro-Ile-Tyr-Arg-Leu-Arg-Tyr-NH2

Sequence:

INPIYRLRY

Cas No. :

Molecular Formula:

C₅₇H₉₁N₁₇O₁₂

Molecular Weight:

1206.46

Description

This modified C-terminal fragment of NPY displaced [3H]NPY bound to rat brain membranes (Y2) with an IC50 = 0.174 uM and inhibited the NPY-induced intracellular calcium release in human erythroleukemia cells (Y1) with an IC50 = 9 nM.

Reference

• J.J.Leban et al., J. Med. Chem., 38, 1150 (1995)