Sequence 3 letters:

Leu-Pro-Phe-Phe-Asp

Sequence:

LPFFD

Cas No. :

Molecular Formula:

C₃₃H₄₃N₅O₈

Molecular Weight:

637.74

Description

The pentapeptide LPFFD (iAβ5), a highly efficient β-sheet breaker, inhibited amyloid formation in vitro, prevented amyloid neurotoxicity in cell culture, reduced in vivo cerebral Aβ deposition and completely blocked amyloid fibril formation in rat brain.

Reference