Sequence 3 letters:

H-Asp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2

Sequence:

H-DVQPPGLKVWSDPF-NH2

Cas No. :

Molecular Formula:

C₇₅H₁₁₀N₁₈O₂₀

Molecular Weight:

1583.78

Description

PNX-14 is a novel neuropeptide, protecting human brain vascular endothelial cells against oxygen-glucose deprivation/reoxygenation (OGD/R)-induced inflammation and permeability, significantly ameliorating HFD-induced obesity and fatty liver, regulating pituitary gonadotropin secretion by modulating the expression of the GnRH receptor.Recent studies indicate PNX-14 is a neuropeptide with potential anti-inflammatory effects in the gastrointestinal tract.

Reference

• Zandeh-Rahimi Y, Panahi N, Hesaraki S, Shirazi-Beheshtiha SH. Protective Effects of Phoenixin-14 Peptide in the Indomethacin-Induced Duodenal Ulcer: An Experimental Study. Int J Pept Res Ther. 2022;28(1):43. doi: 10.1007/s10989-021-10314-9. Epub 2022 Jan 3. PMID: 35002587; PMCID: PMC8722415.