Sequence 3 letters:

H-Thr-Ser-Gly-Pro-Leu-Gly-Asn-Leu-Ala-Glu-Glu-Leu-Asn-Gly-Tyr-Ser-Arg-Lys-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2

Sequence:

TSGPLGNLAEELNGYSRKKGGFSFRF

Cas No. :

Molecular Formula:

C₁₂₇H₁₉₅N₃₇O₃₇

Molecular Weight:

2832.17

Description

P518 (human) is an RF-amide peptide ligand for SP9155, an orphan G-protein-coupled receptor with high homology to orexin, neuropeptide FF and CCK receptors. It has been shown to potently activate SP9155 with an EC50 of 7 nM.

Reference

• N.Chartrei et al., Proc. Natl. Acad. Sci. USA, 100, 15247 (2003)
• Y.Jiang et al., J. Biol. Chem., 278, 27652 (2003)