Sequence 3 letters:

H-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2

Sequence:

SALRHYINLITRQRY

Cas No. :

Molecular Formula:

C₈₅H₁₃₉N₂₉O₂₁

Molecular Weight:

1903.22

Description

This C-terminal fragment of NPY is a more potent inhibitor of calmodulin-stimulated phosphodiesterase than NPY itself. The inhibitory effect obviously depends on the basic amphiphilic helical nature of the fragment.

Reference

• T.Ishiguro et al., Chem. Pharm. Bull., 36, 2720 (1988)