Sequence:

References:

• Groot F,Sanders RW,ter Brake O,Nazmi K,Veerman EC,Bolscher JG,Berkhout B
  J Virol, 2006, 9236-9243
  
  
  Histatin 5-derived peptide with improved fungicidal properties enhances human immunodeficiency virus type 1 replication by promoting viral entry
  
• Helmerhorst EJ,Reijnders IM,van 't Hof W,Veerman EC,Nieuw Amerongen AV
  FEBS Lett, 1999, 105-110
  
  
  A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides
  
• Helmerhorst EJ,Reijnders IM,van't Hof W,Simoons-Smit I,Veerman EC,Amerongen AV
  Antimicrob Agents Chemother, 1999, 702-704
  
  
  Amphotericin B- and fluconazole-resistant Candida spp., Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides
  
• Veerman EC,Valentijn-Benz M,Nazmi K,Ruissen AL,Walgreen-Weterings E,van Marle J,Doust AB,van't Hof W,Bolscher JG,Amerongen AV
  J Biol Chem, 2007, 18831-18841
  
  
  Energy depletion protects Candida albicans against antimicrobial peptides by rigidifying its cell membrane
  
• Rothstein DM,Spacciapoli P,Tran LT,Xu T,Roberts FD,Dalla Serra M,Buxton DK,Oppenheim FG,Friden P
  Antimicrob Agents Chemother, 2001, 1367-1373
  
  
  Anticandida activity is retained in P-113, a 12-amino-acid fragment of histatin 5
  
• Hieshima K,Ohtani H,Shibano M,Izawa D,Nakayama T,Kawasaki Y,Shiba F,Shiota M,Katou F,Saito T,Yoshie O
  J Immunol, 2003, 1452-1461
  
  
  CCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity.
  
• Situ H,Bobek LA
  Antimicrob Agents Chemother, 2000, 1485-1493
  
  
  In vitro assessment of antifungal therapeutic potential of salivary histatin-5, two variants of histatin-5, and salivary mucin (MUC7) domain 1.
  
• Welling MM,Brouwer CP,van 't Hof W,Veerman EC,Amerongen AV
  Antimicrob Agents Chemother, 2007, 3416-3419
  
  
  Histatin-derived monomeric and dimeric synthetic peptides show strong bactericidal activity towards multidrug-resistant Staphylococcus aureus in vivo.
  
• Luque-Ortega JR,van't Hof W,Veerman EC,Saugar JM,Rivas L
  FASEB J, 2008, 1817-1828
  
  
  Human antimicrobial peptide histatin 5 is a cell-penetrating peptide targeting mitochondrial ATP synthesis in Leishmania.
  
• Wanmakok M,Orrapin S,Intorasoot A,Intorasoot S
  Gene, 2018,
  
  
  Expression in Escherichia coli of novel recombinant hybrid antimicrobial peptide AL32-P113 with enhanced antimicrobial activity in vitro.
  
• Portell-Buj E,et al.
  J Med Microbiol, 2018,
  
  
  In vitro activity of 12 antimicrobial peptides against Mycobacterium tuberculosis and Mycobacterium avium clinical isolates.
  
• Conklin SE,Bridgman EC,Su Q,Riggs-Gelasco P,Haas KL,Franz KJ
  Biochemistry, 2017, 4244-4255
  
  
  Specific Histidine Residues Confer Histatin Peptides with Copper-Dependent Activity against Candida albicans.