Sequence 3 letters:

H-Arg-Gly-Asp-Ser-OH

Sequence:

RGDS

Cas No. :

Molecular Formula:

C₁₅H₂₇N₇O₈

Molecular Weight:

433.42

Description

Tetrapeptide which supports fibroblast attachment and inhibits fibronectin binding to platelets. Target sequence for syphilis spirochete cytadherence.

Reference

• M.D.Pierschbacher and E.Ruoslahti, Nature, 309, 30 (1984)
• M.Ginsberg et al., J. Biol. Chem., 260, 3931 (1985)
• D.M.Haverstick et al., Blood, 66, 946 (1985)
• D.D.Thomas et al., J. Exp. Med., 162, 1715 (1985)
• M.E.Carr et al., Thromb. Haemost., 73, 499 (1995)
• R.Ortega-Velazquez et al., FASEB J., 17, 1529 (2003)