Sequence 3 letters

H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gly-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH

Sequence

H-DAEFRHDSGYEVHHQKLVFFAGDVGSNKGAIIGLMVGGVV-OH

Cas No.

175010-18-1

Molecular Formula:

C₁₉₁H₂₉₁N₅₃O₅₆S

Molecular Weight:

4257.83

Purity

95%+ by HPLC

Description

The highly neurotoxic arctic mutant (E22G) of Aβ has been used to study the mechanisms underlying the formation of soluble and insoluble β-amyloid aggregates. As the wild-type Aβ, the arctic mutant preferably assembles in the presence of GM1 ganglioside.

Reference