Galanin (1-13)-Bradykinin (2-9) amide, M35

Not For Human Use, Lab Use Only.

C107H153N27O26

SKU KSP-25568 Category

Sequence 3 letters:

H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2

Sequence:

GWTLNSAGYLLGPPPGFSPFR

Cas No. :

Molecular Formula:

C107H153N27O26

Molecular Weight:

2233.56

Description

This galanin antagonist, which binds with high specificity and affinity to galanin binding sites, has been administered to rats to test the functional consequences of the galanin receptor blockade in a spatial learning task. The results suggest that galanin antagonists might provide a new principle in the treatment of dementia and related disorders.

Reference

  • T.Bartfai et al., Trends Pharmacol. Sci., 13, 312 (1992)
  • S.O.Oegren et al., Neuroscience, 51, 1 (1992)
  • K.Kask et al., Regul. Peptides, 59, 341 (1995)
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