Sequence 3 letters:

H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH

Sequence:

H-GEPPPGKPADDAGLV-OH

Cas No. :

Molecular Formula:

C₆₂H₉₈N₁₆O₂₂

Molecular Weight:

1419.53

Description

BPC (Body Protecting Compound) 157 is derived in the stomach and isolated from human gastric juice. Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants.

Reference

• 1. Chang, Chung-Hsun, et al. “The Promoting Effect of Pentadecapeptide BPC 157 on Tendon Healing Involves Tendon Outgrowth, Cell Survival, and Cell Migration.” Journal of Applied Physiology, vol. 110, no. 3, 2011, pp. 774–780., doi:10.1152/japplphysiol.00945.2010.
• 2. Misra, Monika. “Obesity Pharmacotherapy: Current Perspectives and Future Directions.” Current Cardiology Reviews,
• vol. 9, no. 1, 2013, pp. 33–54., doi:10.2174/157340313805076322.