Sequence 3 letters:

H-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH

Sequence:

H-LVFFAEDVGSNKGAIIGLMVGGVV-OH

Cas No. :

Molecular Formula:

C₁₁₀H₁₇₈N₂₆O₃₁S

Molecular Weight:

2392.86

Description

Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. p3 is a major constituent of diffuse plaques observed in AD brains and pre-amyloid plaques in people affected by Down syndrome.

Reference