β-Amyloid (16-20) 153247-40-6
Not For Human Use, Lab Use Only.
β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility).
Sequence 3 letters
H-Lys-Leu-Val-Phe-Phe-OH
Sequence
H-KLVFF-OH
Cas No.
153247-40-6
Molecular Formula
C35H52N6O6
Molecular Weight
652.84
Purity
95%+by HPLC
Description
β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility)
In Vitro
β-Amyloid peptide(16-20) (-NH2) inhibits Abeta fibril formation under a dose of 1:2 molar ratio (Aβ40/peptide), after incubation for 12 days (37 ℃)[1].
References
[1]. Austen BM, et al. Designing peptide inhibitors for oligomerization and toxicity of Alzheimer’s beta-amyloid peptide. Biochemistry. 2008 Feb 19;47(7):1984-92.