β-Amyloid (1-28) | 109770-29-8
Not For Human Use, Lab Use Only.
β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer’s disease (AD) patients.
Sequence 3 letters
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
Sequence
H-DAEFRHDSGYEVHHQKLVFFAEDVGSNK-OH
Cas No.
109770-29-8
Molecular Formula
C145H209N41O46
Molecular Weight
3262.53
Purity
95%+ by HPLC
Description
The remarkable histochemical features of Alzheimer’s disease (AD) are plaques that contain cores of extracellular filaments, which have been identified as amyloid substance. The major component of this amyloid is the β-protein. The synthetic peptide, having the same sequence as the N-terminal 28 residues, formed fibrils that have the same antigenic and structural features like the native AD amyloid filaments.