Sequence 3 letters:

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln

Sequence:

DAEFRHDSGYEVHHQ

Cas No. :

Molecular Formula:

C₇₈H₁₀₇N₂₅O₂₇

Molecular Weight:

1826.87

Description

Aβ (1-15) was used in a study investigating the presence of conformational epitope/s (mimotope/s) on fibrillar amyloid β-protein (1-42). The N-terminal Aβ fragments Aβ1-14 (H-7372), Aβ1-15, and Aβ1-16 (H-2958) are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The fragments can serve as biomarkers in clinical studies of the effect of such inhibitors.

Reference