February 2024

PROTAC Linkers and their role in developing cancer therapeutics

Introduction  Novel approaches are always being sought in the dynamic field of cancer therapies to tackle the difficulties presented by historically elusive pharmacological targets. A novel strategy that is gaining popularity is the application of Proteolysis-Targeting Chimeras (PROTACs). These molecules have shown tremendous promise in the selective degradation of disease-causing proteins, providing novel therapeutic options…

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